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Sugi Predict / Compounds / (Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL5960443

C(=Cc1ccccc1)c1ccccc1.CC(N)=O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GLA P06280 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.64
▸ HDAC1 Q13547 3/20 0.56
▸ HDAC3 O15379 2/20 0.56
▸ HDAC4 P56524 2/20 0.56
▸ HDAC2 Q92769 2/20 0.56
▸ HDAC8 Q9BY41 2/20 0.56
▸ HDAC6 Q9UBN7 2/20 0.56
▸ PLIN1 O60240 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ MAPT P10636 2/20 0.56
▸ RECQL P46063 2/20 0.56
▸ PLIN5 Q00G26 2/20 0.56
▸ ABHD5 Q8WTS1 2/20 0.56
▸ TNKS O95271 1/20 0.56
▸ HCAR2 Q8TDS4 1/20 0.56
▸ HDAC7 Q8WUI4 1/20 0.56
▸ HDAC10 Q969S8 1/20 0.56
▸ HDAC11 Q96DB2 1/20 0.56
▸ TNKS2 Q9H2K2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL7706161 0.90 GLA (0.70) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL7706163 0.90 GLA (0.70) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL28483617 0.90 HDAC1 (0.61) GLATDP1HDAC1HDAC3HDAC4
Acetamide SCHEMBL11419950 0.89 GLA (0.57) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL8417390 0.87 GLA (0.67) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL8903561 0.87 GLA (0.67) GLATDP1HDAC1HDAC3HDAC4
Cinnamic Acid SCHEMBL4594748 0.87 HCAR2 (0.79) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL28184824 0.85 HDAC1 (0.56) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL980839 0.84 HDAC1 (0.67) GLATDP1HDAC1HDAC3HDAC4
(Z)-1,2-Diphenylethene SCHEMBL4532649 0.84 HDAC1 (0.67) GLATDP1HDAC1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006004722-A2 COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS BIOMOL RESEARCH LABORATORIES, INC. (US) 2006-01-12 — — WO claimed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 — — US disclosed
EP-3280402-A2 FORMULATION AND PROCESS FOR MODULATING WOUND HEALING Biomendics LLC (US) 2018-02-14 — — EP disclosed
CN-105229077-B Electroconductive polymer dispersion liquid and conductive coating 信越聚合物株式会社 2017-06-09 — — CN disclosed
WO-2016164531-A2 FORMULATION AND PROCESS FOR MODULATING WOUND HEALING BioMendics, LLC (US) 2016-10-13 — — WO disclosed
WO-2006004722-A2 COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS BIOMOL RESEARCH LABORATORIES, INC. (US) 2006-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB GLA 1313/4885TDP1 1811/4885HDAC1 420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.