SCHEMBL3343312

SCHEMBL3343312

OC1=CC=CCC1=Nc1ccccn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 3/20 0.39
ADRA2B P18089 3/20 0.39
ADRA2C P18825 3/20 0.39
PLAU P00749 1/20 0.39
NOS3 P29474 2/20 0.38
NOS1 P29475 2/20 0.38
NOS2 P35228 2/20 0.38
MAPT P10636 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 3/20 0.35
HPGD P15428 2/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
HTT P42858 3/20 0.34
KCNH2 Q12809 3/20 0.34
KDM4E B2RXH2 3/20 0.34
OPRK1 P41145 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3845006 0.74 TSHR (0.36) MAPTALDH1A1LMNAHTTKCNH2
SCHEMBL3340989 0.73 ALDH1A1 (0.40) ALDH1A1LMNATDP1NPC1ALOX15
SCHEMBL2035577 0.72 MAPT (0.41) MAPTALDH1A1HSD17B10LMNAHPGD
SCHEMBL3849663 0.71 PTPRA (0.40) MAPTALDH1A1KDM4ESMN1; SMN2L3MBTL1
SCHEMBL3215622 0.67
SCHEMBL2575551 0.66
SCHEMBL3630575 0.64
Dipyridyl SCHEMBL6871734 0.62 KDM4E (0.54) MAPTALDH1A1HSD17B10LMNAHPGD
SCHEMBL4574109 0.61
Dipyridyl SCHEMBL11399183 0.61 KDM4E (0.52) MAPTALDH1A1HSD17B10LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010550-B1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL RES & TECHNOLOGY FELUY (BE) 2013-06-19 EP disclosed
US-8399582-B2 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-03-19 US disclosed
US-8399582-B2 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-03-19 US disclosed
US-20100160583-A1 Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes TOTAL PETROCHEMICALS RESEARCH FEULY (BE) 2010-06-24 US disclosed
US-20100160583-A1 Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes TOTAL PETROCHEMICALS RESEARCH FEULY (BE) 2010-06-24 US disclosed
EP-2010550-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-07 EP disclosed
EP-2010550-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-07 EP disclosed
WO-2007122139-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-11-01 WO disclosed
WO-2007122139-A1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-11-01 WO disclosed
EP-1849791-A1 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-10-31 EP disclosed
EP-1849791-A1 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-10-31 EP disclosed