Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341792 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP1A2TSHRHRH3ALDH1A1 | |
| SCHEMBL3845006 | 0.77 | TSHR (0.36) | CYP1A2MAPTTSHRSLC6A4KDM4E | |
| SCHEMBL3340989 | 0.76 | ALDH1A1 (0.40) | CYP1A2HRH3ALDH1A1NPC1RAB9A | |
| SCHEMBL3845804 | 0.74 | PTPRA (0.39) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3343312 | 0.71 | ADRA2A (0.39) | SMN1; SMN2MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL29785749 | 0.65 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7979864 | 0.65 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL12532007 | 0.65 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1039370 | 0.65 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6921059 | 0.65 | PTPRA (0.63) | PTPRAFDPSGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010550-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122139-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-11-01 | — | — | WO | disclosed |