Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312432 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL59671 | 0.83 | HTR2A (0.60) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL29367221 | 0.83 | HTR2A (0.60) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| Methane SCHEMBL27842569 | 0.81 | HTR2A (0.58) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL83486 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL19065039 | 0.81 | L3MBTL1 (0.70) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL30561171 | 0.81 | L3MBTL1 (0.44) | ALDH1A1HSD17B10CYP1B1HIF1ATSHR | |
| SCHEMBL2121166 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| Ethane SCHEMBL1070226 | 0.79 | HTR2A (0.56) | ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6 | |
| SCHEMBL5665402 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |