Chlorotriphenylmethane

Chlorotriphenylmethane

SCHEMBL3343848

ClC(c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 3/20 0.53
KIF11 P52732 1/20 0.46
CYP1A2 P05177 2/20 0.46
KCNN4 O15554 2/20 0.41
CYP2C9 P11712 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP3A4 P08684 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOTUM Q6P988 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP19A1 P11511 1/20 0.39
PTPN5 P54829 2/20 0.38
MEN1 O00255 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
PTPN1 P18031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12305490 0.92 TSHR (0.52) TSHRALDH1A1KIF11CYP1A2KCNN4
Chlorotriphenylmethane SCHEMBL16781670 0.91 TSHR (0.65) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL461 0.91 TSHR (0.65) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL7567317 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL11237663 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL113884 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL7246540 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL29446246 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL27845684 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9
Chlorotriphenylmethane SCHEMBL28253307 0.88 TSHR (0.61) TSHRALDH1A1CYP1A2KCNN4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076492-B2 Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil CIPLA LIMITED (IN) 2011-12-13 US disclosed
US-20100160643-A1 Process for Preparing Trityl Olmesartan Medoxomil and Olmesartan Medoxomil CIPLA LIMITED (IN) 2010-06-24 US disclosed
EP-2074116-A2 PROCESS FOR PREPARING TRITYL OLMESARTAN MEDOXOMIL AND OLMESARTAN MEDOXOMIL Cipla Limited (IN) 2009-07-01 EP disclosed
WO-2008043996-A2 PROCESS FOR PREPARING TRITYL OLMESARTAN MEDOXOMIL AND OLMESARTAN MEDOXOMIL CIPLA LIMITED (IN) 2008-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160643-A1 Process for Preparing Trityl Olmesartan Medoxomil and Olmesartan Medoxomil MED1, AGTR1, MED12 TSHR 1295/4885ALDH1A1 1100/4885KIF11 2642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.