SCHEMBL3344019

SCHEMBL3344019

CC(C)(C)OC(=O)N1CC(Oc2ccc(-c3ccc(S(C)(=O)=O)cc3F)cc2)C1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.61
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3343666 0.92 GPR119 (0.64) GPR119CYP2C9
SCHEMBL3343300 0.90 GPR119 (0.69) GPR119CYP2C9
SCHEMBL3375494 0.86 GPR119 (0.46) GPR119CYP2C9
SCHEMBL388406 0.80 GPR119 (0.66) GPR119CYP2C9
SCHEMBL25326330 0.78 GPR119 (0.61) GPR119
SCHEMBL3348738 0.78 GPR119 (0.52) GPR119CYP2C9
SCHEMBL29768612 0.78 GPR119 (0.48) GPR119
SCHEMBL29084473 0.78 GPR119 (0.48) GPR119
SCHEMBL16434828 0.77 USP30 (0.52) GPR119
SCHEMBL387485 0.76 GPR119 (0.61) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed