Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.68 |
| ▸ | BLM | P54132 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | NSD2 | O96028 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | MTOR | P42345 | 2/20 | 0.68 |
| ▸ | EGFR | P00533 | 2/20 | 0.68 |
| ▸ | TOP2A | P11388 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ametantrone SCHEMBL29723071 | 1.00 | TOP2B (1.00) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL11041980 | 0.98 | TOP2B (0.97) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL18567079 | 0.93 | TOP2B (0.86) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| Ametantrone SCHEMBL29899532 | 0.93 | TOP2B (0.86) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| Ametantrone SCHEMBL4022 | 0.93 | TOP2B (0.86) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| Ametantrone SCHEMBL31237396 | 0.93 | TOP2B (0.86) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL15277979 | 0.91 | TOP2B (0.83) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL15271304 | 0.91 | TOP2B (0.83) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL1426702 | 0.90 | TOP2B (0.81) | TOP2BLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL29357976 | 0.90 | TOP2B (0.81) | TOP2BLMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9259380-B2 | Means for dyeing and/or matting keratinic fibres containing novel 1,4 diaminoanthraquinone dyes | HENKEL AG & CO. KGAA (DE) | 2016-02-16 | — | — | US | claimed |
| US-20150007851-A1 | MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES | HENKEL AG & CO. KGAA (DE) | 2015-01-08 | — | — | US | claimed |
| US-20230240954-A1 | USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION | L'OREAL (FR) | 2023-08-03 | — | — | US | disclosed |
| US-20220365074-A1 | METHODS AND SYSTEMS FOR DETERMINING VIRUSES SUCH AS CORONAVIRUSES USING pH | ANALIZA, INC. (US) | 2022-11-17 | — | — | US | disclosed |
| US-11401234-B2 | Deuterated compounds and uses thereof | OncoTherics Ventures Limited (GB) | 2022-08-02 | — | — | US | disclosed |
| EP-3558235-B1 | USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION | OREAL (FR) | 2021-09-08 | — | — | EP | disclosed |
| US-10928405-B2 | Devices and methods for determining and/or isolating cells such as circulating cancer or fetal cells | ANALIZA, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| EP-3702783-A1 | METHODS FOR DETERMINING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS | Analiza, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| EP-3702783-A1 | METHODS FOR DETERMINING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS | Analiza, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20200270200-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | OncoTherics Ventures Limited (GB) | 2020-08-27 | — | — | US | disclosed |
| EP-3080341-B1 | METHODS FOR DETERMINING AND/OR ISOLATING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS | ANALIZA INC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-5132327-A | ANTI-CANCER COMPOUNDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-07-21 | — | — | US | disclosed |
| WO-1991006540-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-05-16 | — | — | WO | disclosed |
| WO-1991005824-A1 | ANTI-CANCER COMPOUNDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-05-02 | — | — | WO | disclosed |
| EP-0170290-B1 | AMINO-ANTHRACENEDIONES-PLATINUM COMPLEXES USEFUL AS ANTI-CANCER COMPOUNDS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4732893-A | ANTITUMOR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1988-03-22 | — | — | US | disclosed |
| US-4715993-A | FROM SALTS, USING AMMONIA OR METHYLAMINE | AMERICAN CYANAMID COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0170290-A2 | Amino-anthracenediones-platinum complexes useful as anti-cancer compounds | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-02-05 | — | — | EP | disclosed |
| US-4526788-A | Polymeric[[(oxazolidinyl)alkyl]amino]anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0122417-A2 | Polymeric(((oxazolidinyl)alkyl)amino)anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150007851-A1 | MEANS FOR DYEING AND/OR MATTING KERATINIC FIBRES CONTAINING NOVEL 1,4 DIAMINOANTHRAQUINONE DYES | KRT18, SAT1, KIF5A | TOP2B 954/4885LMNA 920/4885MEN1 1473/4885 |
| US-20230240954-A1 | USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION | KRT18, CUTA, KLK5 | TOP2B 989/4885LMNA 266/4885MEN1 2794/4885 |
| US-11401234-B2 | Deuterated compounds and uses thereof | HIF1AN, HIF1A, EGLN2 | TOP2B 208/4885LMNA 1245/4885MEN1 2862/4885 |
| US-20200270200-A1 | DEUTERATED COMPOUNDS AND USES THEREOF | HIF1AN, HIF1A, EGLN2 | TOP2B 208/4885LMNA 1245/4885MEN1 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.