KIF5A — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3333345	0.58	1/20
SCHEMBL3329830	0.57	1/20
SCHEMBL11939079	0.55	1/20
SCHEMBL27775392	0.55	1/20
SCHEMBL3329866	0.54	1/20
SCHEMBL27796460	0.54	1/20
SCHEMBL301188	0.54	1/20
SCHEMBL3336116	0.54	1/20
SCHEMBL301157	0.51	1/20
SCHEMBL3333434	0.51	1/20
SCHEMBL3334412	0.50	1/20
SCHEMBL3334609	0.50	1/20
SCHEMBL296230	0.49	1/20
SCHEMBL27775753	0.47	1/20
SCHEMBL12288088	0.44	1/20
SCHEMBL300839	0.42	1/20
SCHEMBL22560009	0.42	1/20
SCHEMBL300818	0.42	1/20

Clinical trials — most relevant to KIF5A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study	PHASE3	COMPLETED
Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder	PHASE3	COMPLETED
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill	nan	UNKNOWN
Peripheral Neurofilament Levels and Amyotrophic Lateral Sclerosis	nan	COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Spastic Paraplegia - Centers of Excellence Research Network	nan	RECRUITING
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium	nan	COMPLETED
Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS)	nan	UNKNOWN
Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients	nan	COMPLETED
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD	nan	ENROLLING_BY_INVITATION
Brain Involvement in Dystrophinopathies Part 2	nan	COMPLETED
The Crosstalk Between the Epigenome and Mitochondria in SCI	nan	NOT_YET_RECRUITING
White Matter Integrity According to BDNF Genotype After Stroke	nan	COMPLETED
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
Autologous Stem/Stromal Cells in Neurological Disorders and Disease	nan	UNKNOWN
Does Spinal Manipulation Therapy Impact Lumbar Proprioception	nan	COMPLETED
3 Year Follow up on ANO5 Patients	nan	ACTIVE_NOT_RECRUITING
Perineural Injection and Supraspinatus Tendenopathy	nan	UNKNOWN
Evolution of the Functional and Muscular State of Patients With Muscular Dystrophy 2A Belts	nan	ACTIVE_NOT_RECRUITING
Comparison of Scapular Stabilization and Thoracic Extension Exercises in Patients With Scapular Dyskinesis	nan	COMPLETED
3D-Microscopic Muscle Architecture in Cerebral Palsy	nan	RECRUITING
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
Molecular Biomarkers Associated With Degenerative Joint Disease in the Knee	nan	COMPLETED
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development	nan	COMPLETED
Pilot Study on Caffeine Efficiency in ADCY5-related Dyskinesia	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a KIF5A binder may also engage these)

Protein	Name	Similarity
Q5R9K7	—	1.000	Q5R9K7 →
P28738	—	1.000	P28738 →
Q91785	—	1.000	Q91785 →
Q6QLM7	—	1.000	Q6QLM7 →
P33175	—	1.000	P33175 →
KIF5B	Kinesin-1 heavy chain	1.000	landscape →
KIF5C	Kinesin heavy chain isoform 5C	1.000	landscape →
P56536	—	1.000	P56536 →
P21613	—	1.000	P21613 →
P35978	—	1.000	P35978 →
P34540	—	1.000	P34540 →
Q86VH2	—	1.000	Q86VH2 →
Q2PQA9	—	0.999	Q2PQA9 →
P17210	—	0.999	P17210 →
KIF15	Kinesin-like protein KIF15	0.998	landscape →
F4IIS5	—	0.998	F4IIS5 →
B3H6Z8	—	0.997	B3H6Z8 →
P46863	—	0.997	P46863 →
Q2VIQ3	—	0.997	Q2VIQ3 →
Q9AWM8	—	0.997	Q9AWM8 →
Q498L9	—	0.996	Q498L9 →
Q61768	—	0.996	Q61768 →
Q7Z4S6	—	0.996	Q7Z4S6 →
Q90640	—	0.996	Q90640 →
Q8GS71	—	0.995	Q8GS71 →
Q9H1H9	—	0.995	Q9H1H9 →
Q9GYZ0	—	0.995	Q9GYZ0 →
Q5U312	—	0.995	Q5U312 →
Q9QXL2	—	0.994	Q9QXL2 →
UACA	Uveal autoantigen with coiled-coil domains and ankyrin repeats	0.994	landscape →