Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338348 | 0.88 | TSHR (0.62) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL16495328 | 0.88 | TSHR (0.62) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL2484395 | 0.88 | TSHR (0.62) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL4851304 | 0.87 | PKM (0.55) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL2485226 | 0.86 | ACHE (0.61) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL2483775 | 0.86 | ACHE (0.61) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL13338340 | 0.86 | ACHE (0.61) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL11619459 | 0.84 | L3MBTL1 (0.65) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL11619637 | 0.84 | L3MBTL1 (0.65) | L3MBTL1PKMALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11619986 | 0.82 | L3MBTL1 (0.67) | L3MBTL1PKMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | L3MBTL1 2853/4885PKM 4614/4885ALDH1A1 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.