Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344785 | 0.88 | CA1 (0.47) | TYMSPOLBCA1CA2DAO | |
| SCHEMBL14604111 | 0.83 | GAA (0.45) | RAB9ASMN1; SMN2DAO | |
| SCHEMBL16486420 | 0.80 | TSHR (0.43) | TYMSRAB9ADAO | |
| SCHEMBL16880522 | 0.79 | KMT2A (0.56) | TYMSRAB9APOLB | |
| SCHEMBL4649050 | 0.79 | PNP (0.42) | DAOLMNA | |
| SCHEMBL7268031 | 0.78 | SRD5A2 (0.54) | DAOMRGPRX4 | |
| SCHEMBL6471052 | 0.77 | RNASEH1 (0.47) | — | |
| SCHEMBL1586483 | 0.77 | DAO (0.44) | DAO | |
| SCHEMBL16487097 | 0.75 | POLB (0.39) | RAB9ANPC1POLBCA1CA2 | |
| SCHEMBL11464459 | 0.74 | CA1 (0.77) | PTPN5RAB9ASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042642-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2010-04-15 | — | — | WO | disclosed |