Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.72 |
| ▸ | NPC1 | O15118 | 11/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | KDM5A | P29375 | 1/20 | 0.58 |
| ▸ | KDM5C | P41229 | 1/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346059 | 0.85 | RAB9A (0.72) | RAB9ANPC1KDM4EPOLBHDAC2 | |
| SCHEMBL18773997 | 0.84 | NPC1 (1.00) | RAB9ANPC1KDM4EPOLBHDAC2 | |
| SCHEMBL14292560 | 0.83 | RAB9A (0.65) | RAB9ANPC1KDM4EPOLBHDAC2 | |
| SCHEMBL16900376 | 0.81 | RAB9A (1.00) | RAB9ANPC1POLBHDAC2HDAC8 | |
| SCHEMBL4436883 | 0.81 | NPC1 (0.67) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL7282271 | 0.81 | HDAC2 (0.78) | RAB9ANPC1KDM4EHDAC2HDAC8 | |
| SCHEMBL3344982 | 0.80 | RAB9A (0.76) | RAB9ANPC1KDM4EPOLBHDAC2 | |
| SCHEMBL3351696 | 0.80 | HDAC2 (0.52) | RAB9ANPC1KDM4EPOLBHDAC2 | |
| SCHEMBL4895817 | 0.80 | TPMT (0.53) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL475666 | 0.79 | MCHR1 (0.58) | RAB9ANPC1KDM4EPOLBHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |