Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.76 |
| ▸ | NPC1 | O15118 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475666 | 0.82 | MCHR1 (0.58) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL3345017 | 0.80 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3351696 | 0.78 | HDAC2 (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL3346059 | 0.78 | RAB9A (0.72) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3349870 | 0.77 | HDAC2 (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7705708 | 0.74 | ALDH1A1 (0.76) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7282271 | 0.74 | HDAC2 (0.78) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3645315 | 0.73 | MCHR1 (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11822961 | 0.72 | ALDH1A1 (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| Iodide SCHEMBL9011168 | 0.72 | HDAC2 (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |