Sugi Predict

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SCHEMBL4436883

SCHEMBL4436883

Cc1ccc(CCNC(=O)c2cc(C)cc(C)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.67
▸ RAB9A P51151 4/20 0.67
▸ POLB P06746 2/20 0.66
▸ KDM4E B2RXH2 1/20 0.66
▸ SMN1; SMN2 Q16637 2/20 0.63
▸ MAPT P10636 4/20 0.58
▸ MAPK1 P28482 1/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.57
▸ LMNA P02545 2/20 0.57
▸ TP53 P04637 2/20 0.57
▸ TRPV1 Q8NER1 1/20 0.56
▸ ALDH1A1 P00352 2/20 0.53
▸ GAA P10253 1/20 0.53
▸ ESRRG P62508 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13389169 0.89 NPC1 (0.64) NPC1RAB9APOLBKDM4ESMN1; SMN2
SCHEMBL14469162 0.88 NPC1 (0.84) NPC1RAB9APOLBSMN1; SMN2MAPT
SCHEMBL13389193 0.86 MAPT (0.61) NPC1RAB9APOLBKDM4ESMN1; SMN2
SCHEMBL13389443 0.86 KDM4E (0.58) NPC1RAB9APOLBKDM4ESMN1; SMN2
SCHEMBL5969191 0.83 RAB9A (0.88) NPC1RAB9APOLBSMN1; SMN2MAPT
SCHEMBL8432669 0.82 POLB (0.62) NPC1RAB9APOLBKDM4EMAPT
SCHEMBL3345017 0.81 RAB9A (0.72) NPC1RAB9APOLBKDM4ESMN1; SMN2
SCHEMBL15679867 0.81 NPC1 (0.72) NPC1RAB9APOLBSMN1; SMN2MAPT
SCHEMBL31424939 0.80 HDAC8 (0.76) NPC1RAB9APOLBSMN1; SMN2MAPT
SCHEMBL16900376 0.80 RAB9A (1.00) NPC1RAB9APOLBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 — — US disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 — — EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 — — EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 — — US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 — — EP disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 — — EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 — — EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 — — EP disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 — — EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 — — US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 NPC1 3616/4885RAB9A 1685/4885POLB 1853/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 NPC1 4327/4885RAB9A 1698/4885POLB 1388/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 NPC1 4327/4885RAB9A 1698/4885POLB 1388/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 NPC1 4327/4885RAB9A 1716/4885POLB 2113/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN NPC1 3813/4885RAB9A 2720/4885POLB 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.