Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 9/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344793 | 0.93 | PTGDR2 (0.58) | PTGDR2CHRM1RORCKLKB1CYP3A4 | |
| SCHEMBL3351455 | 0.90 | PTGDR2 (0.43) | PTGDR2CHRM1RORCKLKB1CYP3A4 | |
| SCHEMBL3344721 | 0.84 | P2RX3 (0.42) | PTGDR2KDM4EJAK2 | |
| SCHEMBL2571339 | 0.84 | PTGDR2 (0.50) | PTGDR2CHRM1KDM4EJAK2RORC | |
| SCHEMBL3345546 | 0.82 | PTGDR2 (0.50) | PTGDR2CHRM1RORCKLKB1CYP3A4 | |
| SCHEMBL2575061 | 0.82 | PTGDR2 (0.56) | PTGDR2RORC | |
| SCHEMBL3346044 | 0.81 | TSHR (0.37) | PTGDR2KDM4EJAK2 | |
| SCHEMBL2570536 | 0.81 | PTGDR2 (0.56) | PTGDR2CHRM1KDM4EJAK2RORC | |
| SCHEMBL2570380 | 0.80 | PTGDR2 (0.55) | PTGDR2CHRM1RORC | |
| SCHEMBL2568426 | 0.79 | PTGDR2 (0.62) | PTGDR2CHRM1RORCKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |