Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423750 | 0.92 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL3351438 | 0.89 | TSHR (0.41) | TSHRPTGDR2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3344721 | 0.89 | P2RX3 (0.42) | PTGDR2GAAALDH1A1KDM4EHPGD | |
| SCHEMBL3345117 | 0.81 | PTGDR2 (0.50) | PTGDR2KDM4EJAK2 | |
| SCHEMBL3348846 | 0.81 | TSHR (0.36) | TSHRPTGDR2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL13423755 | 0.80 | PTGDR2 (0.44) | TSHRPTGDR2 | |
| SCHEMBL3345051 | 0.80 | P2RX3 (0.42) | TSHRPTGDR2P2RX3 | |
| SCHEMBL534018 | 0.78 | PTGDR2 (0.44) | TSHRPTGDR2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3778423 | 0.76 | PTGDR2 (0.41) | TSHRPTGDR2GAASMN1; SMN2RAB9A | |
| SCHEMBL534205 | 0.74 | PTGDR2 (0.38) | TSHRPTGDR2GAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |