Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 11/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345546 | 0.93 | PTGDR2 (0.50) | PTGDR2RORCCHRM1SCN9AKLKB1 | |
| SCHEMBL3345117 | 0.90 | PTGDR2 (0.50) | PTGDR2RORCCHRM1KLKB1CYP3A4 | |
| SCHEMBL2576335 | 0.84 | PTGDR2 (0.43) | PTGDR2RORCCHRM1SCN9AKLKB1 | |
| SCHEMBL3344793 | 0.82 | PTGDR2 (0.58) | PTGDR2RORCCHRM1KLKB1CYP3A4 | |
| SCHEMBL2568427 | 0.82 | RORC (0.48) | PTGDR2RORC | |
| SCHEMBL3351438 | 0.81 | TSHR (0.41) | PTGDR2RORC | |
| SCHEMBL2574623 | 0.81 | PTGDR2 (0.46) | PTGDR2RORCSCN9AKLKB1 | |
| SCHEMBL2573811 | 0.79 | PTGDR2 (0.52) | PTGDR2RORC | |
| SCHEMBL2573441 | 0.77 | PTGDR2 (0.46) | PTGDR2RORCCHRM1SCN9A | |
| SCHEMBL3344721 | 0.77 | P2RX3 (0.42) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |