Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344730 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL3779299 | 0.80 | DAO (0.40) | ALDH1A1MEN1MAPTKMT2APTGS1 | |
| SCHEMBL3349053 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL3351508 | 0.78 | PTGS2 (0.37) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL3345068 | 0.74 | CYP2C9 (0.41) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL3344884 | 0.73 | SLC2A1 (0.39) | ALDH1A1MEN1MAPTKMT2APTGS1 | |
| SCHEMBL3344758 | 0.72 | PTGDR2 (0.51) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL3345086 | 0.72 | ALKBH3 (0.42) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL14315177 | 0.72 | ERAP1 (0.43) | ALDH1A1MEN1MAPTKMT2AGRIN1 | |
| SCHEMBL3345122 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |