SCHEMBL3345461

SCHEMBL3345461

COC(=O)C=C(COc1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl)OC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
NTRK1 P04629 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360174 1.00 LMNA (0.31) LMNANTRK1
SCHEMBL13941841 1.00 LMNA (0.31) LMNANTRK1
SCHEMBL4152536 0.93 NTRK1 (0.32) LMNANTRK1
SCHEMBL4159307 0.93 NTRK1 (0.32) LMNANTRK1
SCHEMBL4152540 0.93 NTRK1 (0.32) LMNANTRK1
SCHEMBL15229262 0.91 LMNA (0.31) LMNA
SCHEMBL15229264 0.91 LMNA (0.31) LMNA
SCHEMBL9857318 0.87 LMNA (0.44) LMNA
SCHEMBL38952 0.85 TDP1 (0.36) LMNA
SCHEMBL4898211 0.85 TDP1 (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046420-A2 USE OF PROTOPORPHYRINOGEN OXIDASE INHIBITORS ON CULTIVATED PLANTS BASF SE (DE) 2010-04-29 WO claimed
EP-3247213-A1 TERNARY HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL BASF Agro B.V. (NL) 2017-11-29 EP disclosed
WO-2016116531-A1 TERNARY HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL BASF Agro B.V. (NL) 2016-07-28 WO disclosed
WO-2010046420-A2 USE OF PROTOPORPHYRINOGEN OXIDASE INHIBITORS ON CULTIVATED PLANTS BASF SE (DE) 2010-04-29 WO disclosed