SCHEMBL4159307

SCHEMBL4159307

COC(=CC(=O)O)COc1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 9/20 0.32
LMNA P02545 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4152540 1.00 NTRK1 (0.32) NTRK1LMNACNR2
SCHEMBL4152536 1.00 NTRK1 (0.32) NTRK1LMNACNR2
SCHEMBL13941841 0.93 LMNA (0.31) NTRK1LMNA
SCHEMBL3345461 0.93 LMNA (0.31) NTRK1LMNA
SCHEMBL29360174 0.93 LMNA (0.31) NTRK1LMNA
SCHEMBL26135450 0.90 NTRK1 (0.31) NTRK1LMNA
SCHEMBL9857318 0.87 LMNA (0.44) LMNA
SCHEMBL38952 0.87 TDP1 (0.36) LMNA
SCHEMBL4898211 0.87 TDP1 (0.36) LMNA
SCHEMBL15229264 0.86 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3568016-B1 MICROCAPSULES COMPRISING CINMETHYLIN IN THE CORE AND A POLYUREA DERIVED FROM DIPHENYLMETHANE DIISOCYANATE OR AN OLIGOMER THEREOF BASF AGRO BV (NL) 2024-07-17 EP claimed
WO-2024012905-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2024-01-18 WO claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 US claimed
EP-3957176-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS, HERBICIDAL COMPOSITION AND METHOD FOR CONTROLLING UNDESIRABLE VEGETATION BASF Agro B.V. (NL) 2022-02-23 EP claimed
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) BASF SE (DE) 2021-05-20 US claimed
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2021-05-06 US claimed
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2021-03-25 US claimed
EP-3723485-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2020-10-21 EP claimed
EP-3618629-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2020-03-11 EP claimed
WO-2019115511-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2019-06-20 WO claimed
US-20190110480-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2019-04-18 US claimed
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US claimed
US-20180368411-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS BASF SE (DE) 2018-12-27 US claimed
WO-2018202428-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2018-11-08 WO claimed
US-9999222-B2 Herbicidal combination comprising azines BASF SE (DE) 2018-06-19 US claimed
EP-3205208-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES BASF SE (DE) 2017-08-16 EP claimed
EP-3133920-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-03-01 EP claimed
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2017-02-16 US claimed
WO-2015162164-A1 HERBICIDAL COMBINATION COMPRISING AZINES BASF SE (DE) 2015-10-29 WO claimed
EP-1961304-A1 High efficiency formulation with a reduced environmental impact Isagro Ricerca S.r.l. (IT) 2008-08-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH NTRK1 3364/4885LMNA 4193/4885CNR2 1731/4885
US-20210127674-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, TH NTRK1 3364/4885LMNA 4193/4885CNR2 1731/4885
US-20210145003-A1 MIXTURES COMPRISING A HERBICIDE AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLOCOLATE (DMPG) GLO1, DDT, GMDS NTRK1 3760/4885LMNA 2463/4885CNR2 2588/4885
US-20210084902-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES TH, CASP3, PIK3C3 NTRK1 3716/4885LMNA 4428/4885CNR2 2798/4885
US-20180368411-A1 METHOD FOR CONTROLLING HERBICIDE RESISTANT OR TOLERANT WEEDS CYP8B1, DDT, NOTUM NTRK1 3948/4885LMNA 4450/4885CNR2 1129/4885
US-20170042154-A1 HERBICIDAL COMBINATION COMPRISING AZINES CBR3, CBR1, DDT NTRK1 1038/4885LMNA 2939/4885CNR2 175/4885
US-20190110480-A1 MIXTURES AND COMPOSITIONS COMPRISING PAENIBACILLUS STRAINS OR FUSARICIDINS AND CHEMICAL PESTICIDES PFAS, PEF1, PGLS NTRK1 4521/4885LMNA 3787/4885CNR2 4234/4885
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, SNX3, SFXN3 NTRK1 4413/4885LMNA 4259/4885CNR2 4818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.