SCHEMBL4152540

SCHEMBL4152540

CO/C(=C\C(=O)O)COc1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 9/20 0.32
LMNA P02545 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4159307 1.00 NTRK1 (0.32) NTRK1LMNACNR2
SCHEMBL4152536 1.00 NTRK1 (0.32) NTRK1LMNACNR2
SCHEMBL13941841 0.93 LMNA (0.31) NTRK1LMNA
SCHEMBL3345461 0.93 LMNA (0.31) NTRK1LMNA
SCHEMBL29360174 0.93 LMNA (0.31) NTRK1LMNA
SCHEMBL26135450 0.90 NTRK1 (0.31) NTRK1LMNA
SCHEMBL9857318 0.87 LMNA (0.44) LMNA
SCHEMBL38952 0.87 TDP1 (0.36) LMNA
SCHEMBL4898211 0.87 TDP1 (0.36) LMNA
SCHEMBL15229264 0.86 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090029857-A1 Synergistic Herbicidal Compositions ISAGRO RICERCA S.R.L. (IT) 2009-01-29 US claimed
EP-1998616-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS Isagro Ricerca S.r.l. (IT) 2008-12-10 EP claimed
EP-1961304-A1 High efficiency formulation with a reduced environmental impact Isagro Ricerca S.r.l. (IT) 2008-08-27 EP claimed
WO-2007101587-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.R.L. (IT) 2007-09-13 WO claimed
EP-2387886-B1 BIOCIDE COMPOSITIONS COMPRISING ISOAMYL LACTATE COGNIS IP MAN GMBH (DE) 2016-01-06 EP disclosed
US-20090029857-A1 Synergistic Herbicidal Compositions ISAGRO RICERCA S.R.L. (IT) 2009-01-29 US disclosed
EP-1998616-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS Isagro Ricerca S.r.l. (IT) 2008-12-10 EP disclosed
EP-1961304-A1 High efficiency formulation with a reduced environmental impact Isagro Ricerca S.r.l. (IT) 2008-08-27 EP disclosed
EP-1961304-A1 High efficiency formulation with a reduced environmental impact Isagro Ricerca S.r.l. (IT) 2008-08-27 EP disclosed
WO-2007101587-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.R.L. (IT) 2007-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090029857-A1 Synergistic Herbicidal Compositions DDT, ACHE, CAT NTRK1 4150/4885LMNA 4612/4885CNR2 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.