Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345040 | 0.92 | PTGDR2 (0.39) | KDM4EPTGDR2P2RX3PLA2G2ALMNA | |
| SCHEMBL3345114 | 0.91 | PTGDR2 (0.53) | KDM4EPTGDR2P2RX3PLA2G2ALMNA | |
| SCHEMBL3346140 | 0.85 | PTGDR2 (0.38) | KDM4EPTGDR2P2RX3LMNAALDH1A1 | |
| SCHEMBL3344376 | 0.82 | PLA2G2A (0.55) | PTGDR2P2RX3PLA2G2ALMNAHTT | |
| SCHEMBL3345462 | 0.81 | PLA2G2A (0.45) | KDM4EPTGDR2P2RX3PLA2G2ALMNA | |
| SCHEMBL3344745 | 0.81 | PTGDR2 (0.48) | KDM4EPTGDR2P2RX3PLA2G2ALMNA | |
| SCHEMBL3348106 | 0.76 | PTGDR2 (0.49) | KDM4EPTGDR2P2RX3PLA2G2ALMNA | |
| SCHEMBL3344656 | 0.75 | TP53 (0.41) | KDM4EPTGDR2LMNAALDH1A1HPGD | |
| SCHEMBL5328927 | 0.75 | PTGDR2 (0.64) | KDM4EPTGDR2ALDH1A1HPGDMAPT | |
| SCHEMBL3775770 | 0.73 | PLA2G2A (0.45) | KDM4EPLA2G2ALMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |