Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499879 | 0.78 | MAOA (0.46) | SIRT2HPGDALDH1A1NPC1MAPT | |
| SCHEMBL28763709 | 0.78 | RAD52 (0.40) | SERPINE1 | |
| SCHEMBL27821033 | 0.77 | ALOX5 (0.42) | SERPINE1NOTUMCYP3A4AKR1B10AKR1B1 | |
| SCHEMBL27684522 | 0.77 | RAD52 (0.39) | SERPINE1NOTUMCYP3A4SIRT2AKR1B10 | |
| SCHEMBL27821092 | 0.77 | MAOB (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27742545 | 0.76 | TYR (0.41) | SERPINE1HSD17B10CYP3A4AKR1B10AKR1B1 | |
| SCHEMBL27949329 | 0.75 | HPGD (0.50) | SIRT2USP2HPGDALDH1A1 | |
| SCHEMBL3740782 | 0.75 | CYP4F2 (0.51) | HSD17B10HPGDALDH1A1 | |
| SCHEMBL27652695 | 0.75 | MEP1B (0.45) | NOTUMSIRT2USP2HPGDALDH1A1 | |
| SCHEMBL27585879 | 0.74 | MEN1 (0.50) | HSD17B10CYP3A4SIRT2AKR1B1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| CN-101952244-A | PGD 2The N of acceptor, N-disubstituted amido alkyl biphenyl antagonist | AMIRA PHARMACEUTICALS INC | 2011-01-19 | — | — | CN | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | SERPINE1 4568/4885HSD17B10 278/4885NOTUM 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.