Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31601844 | 0.89 | SLC6A1 (0.35) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Trifluoroacetic Acid SCHEMBL2379448 | 0.89 | SLC6A1 (0.35) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Trifluoroacetic Acid SCHEMBL2378662 | 0.89 | SLC6A1 (0.35) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Trifluoroacetic Acid SCHEMBL28132681 | 0.86 | KDM1A (0.35) | KDM1ADPP4DPP8 | |
| Pivalate SCHEMBL28484105 | 0.85 | GABRP (0.39) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Trifluoroacetic Acid SCHEMBL3758972 | 0.81 | TSHR (0.43) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Trifluoroacetic Acid SCHEMBL14743994 | 0.80 | DPP4 (0.36) | DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL17500734 | 0.80 | SLC6A2 (0.32) | KDM1ADPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL2394605 | 0.79 | SLC6A1 (0.42) | TSHRDPP4DPP8CPN1CPB2 | |
| Trifluoroacetic Acid SCHEMBL2377040 | 0.79 | SLC6A1 (0.42) | TSHRDPP4DPP8CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025110815-A1 | IMIDAZO [1,2-B] PYRIDAZINE-BASED NOVEL COMPOUND AS CDK INHIBITOR AND USE THEREOF | 아이리드비엠에스 주식회사 | 2025-05-30 | — | — | WO | disclosed |
| CN-116057061-A | USP7 inhibitors | 首药控股(北京)股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115215883-A | USP7 inhibitors | 首药控股(北京)股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114907368-A | USP7 inhibitors | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114656479-A | USP7 inhibitor | 首药控股(北京)股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114539283-A | USP7 inhibitor | 首药控股(北京)股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2022048498-A1 | USP7 INHIBITOR | 首药控股(北京)股份有限公司 | 2022-03-10 | — | — | WO | disclosed |
| WO-2020243027-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2020-12-03 | — | — | WO | disclosed |
| CN-107207435-B | Process for preparing 4-cyanopiperidine hydrochloride | 拜耳作物科学股份公司 | 2020-05-19 | — | — | CN | disclosed |
| EP-3245190-B1 | METHOD FOR PREPARING 4-CYANOPIPERIDINE HYDROCHLORIDE | BAYER CROPSCIENCE AG (DE) | 2018-12-26 | — | — | EP | disclosed |
| EP-3245190-A1 | METHOD FOR PREPARING 4-CYANOPIPERIDINE HYDROCHLORIDE | Bayer CropScience Aktiengesellschaft (DE) | 2017-11-22 | — | — | EP | disclosed |
| CN-107207435-A | Process for preparing 4-cyanopiperidine hydrochloride | 拜耳作物科学股份公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2016113277-A1 | METHOD FOR PREPARING 4-CYANOPIPERIDINE HYDROCHLORIDE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-21 | — | — | WO | disclosed |
| US-8097610-B2 | Derivative having PPAR agonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-7888374-B2 | Inhibitors of c-jun N-terminal kinases | ABBOTT LABORATORIES (US) | 2011-02-15 | — | — | US | disclosed |
| US-20090286974-A1 | Derivative having ppar agonistic activity | SHIONOGI & CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| CN-101228127-A | Novel Piperidine Derivatives | BANYU PHARMA CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | MAPKAPK3, MAP3K3, MAPK3 | GABRP 3681/4885GABRD 2449/4885GABRA1 4084/4885 |
| US-20090286974-A1 | Derivative having ppar agonistic activity | PPARD, PPARA, PPARG | GABRP 634/4885GABRD 398/4885GABRA1 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.