Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848616 | 0.79 | HTR2B (0.32) | HTR2BHTR5AABL1PIK3CDPRKDC | |
| SCHEMBL3341800 | 0.78 | PDE4D (0.33) | MAPK14 | |
| SCHEMBL14266198 | 0.63 | ABL1 (0.52) | HTR2BHTR5AABL1MAPK9MAPK10 | |
| SCHEMBL28047085 | 0.62 | MAPK9 (0.54) | HTR2BHTR5AMAPK9MAPK10MAPK14 | |
| SCHEMBL7832387 | 0.62 | CYP11B2 (0.58) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL884693 | 0.61 | CYP11B1 (0.50) | MAPK9MAPK10MAPK8CYP17A1CYP19A1 | |
| Methyl Alcohol SCHEMBL27609603 | 0.61 | ESR1 (0.44) | CYP17A1CYP19A1CYP11B1CYP11B2ESR1 | |
| SCHEMBL7496513 | 0.61 | CYP17A1 (0.47) | HTR2BHTR5AMAPK9MAPK10MAPK8 | |
| SCHEMBL9988734 | 0.60 | MAPK9 (0.55) | HTR2BHTR5AMAPK9MAPK10MAPK14 | |
| SCHEMBL4094629 | 0.59 | KDM4E (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010550-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL RES & TECHNOLOGY FELUY (BE) | 2013-06-19 | — | — | EP | disclosed |
| US-8399582-B2 | Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-03-19 | — | — | US | disclosed |
| US-20100160583-A1 | Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes | TOTAL PETROCHEMICALS RESEARCH FEULY (BE) | 2010-06-24 | — | — | US | disclosed |
| EP-1849791-A1 | Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-10-31 | — | — | EP | disclosed |