Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14266198 | 0.63 | ABL1 (0.52) | HTR2BHTR5AABL1MAPK9MAPK10 | |
| SCHEMBL3343312 | 0.62 | ADRA2A (0.39) | NPC1HSP90AA1L3MBTL1 | |
| SCHEMBL28047085 | 0.62 | MAPK9 (0.54) | HTR2BHTR5AMAPK9MAPK10MAPK14 | |
| Methyl Alcohol SCHEMBL27609603 | 0.61 | ESR1 (0.44) | CYP17A1CYP19A1CYP11B1CYP11B2ESR1 | |
| SCHEMBL7496513 | 0.61 | CYP17A1 (0.47) | HTR2BHTR5AMAPK9MAPK10MAPK8 | |
| SCHEMBL9988734 | 0.60 | MAPK9 (0.55) | HTR2BHTR5AMAPK9MAPK10MAPK14 | |
| SCHEMBL4094629 | 0.59 | KDM4E (0.61) | NPC1HSP90AA1RAB9AL3MBTL1 | |
| SCHEMBL16805042 | 0.59 | ABL1 (0.49) | HTR2BHTR5AABL1MAPK9MAPK10 | |
| SCHEMBL12304121 | 0.59 | ALDH1A1 (0.39) | NPC1RAB9A | |
| SCHEMBL31032063 | 0.58 | PARP1 (0.51) | MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010550-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122139-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-11-01 | — | — | WO | disclosed |