Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423755 | 0.92 | PTGDR2 (0.44) | TSHRPTGDR2RORC | |
| SCHEMBL3346044 | 0.89 | TSHR (0.37) | TSHRGAASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3344721 | 0.81 | P2RX3 (0.42) | GAAALDH1A1L3MBTL1PTGDR2KDM4E | |
| SCHEMBL3345008 | 0.81 | P2RX3 (0.43) | TSHRGAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3351455 | 0.81 | PTGDR2 (0.43) | PTGDR2RORC | |
| SCHEMBL3772935 | 0.81 | TSHR (0.41) | TSHRGAASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3345372 | 0.81 | TDP1 (0.44) | TSHRPTGDR2LMNARORC | |
| SCHEMBL13423750 | 0.80 | PTGDR2 (0.44) | PTGDR2RORC | |
| SCHEMBL3778548 | 0.80 | TSHR (0.42) | TSHRGAASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3780994 | 0.78 | TSHR (0.42) | TSHRGAASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |