Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.46 |
| ▸ | LIPE | Q05469 | 7/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350669 | 1.00 | MGLL (0.53) | MGLLSCN9ALIPEBCHEFAAH | |
| SCHEMBL3346359 | 1.00 | MGLL (0.53) | MGLLSCN9ALIPEBCHEFAAH | |
| SCHEMBL2428762 | 0.90 | MGLL (0.53) | MGLLSCN9ALIPEBCHE | |
| SCHEMBL2429281 | 0.90 | MGLL (0.53) | MGLLSCN9ALIPEBCHE | |
| SCHEMBL2425259 | 0.90 | MGLL (0.53) | MGLLSCN9ALIPEBCHE | |
| SCHEMBL3347799 | 0.87 | MGLL (0.49) | MGLLSCN9A | |
| SCHEMBL3348224 | 0.87 | MGLL (0.49) | MGLLSCN9ALIPEFAAH | |
| SCHEMBL3238559 | 0.87 | SCN9A (0.55) | MGLLSCN9ALIPEBCHEFAAH | |
| SCHEMBL2423585 | 0.85 | FAAH (0.62) | MGLLSCN9ALIPEFAAH | |
| SCHEMBL2429580 | 0.85 | FAAH (0.62) | MGLLSCN9ALIPEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |