Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | LIPE | Q05469 | 11/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428762 | 1.00 | MGLL (0.53) | MGLLLIPEBCHESCN9A | |
| SCHEMBL2429281 | 1.00 | MGLL (0.53) | MGLLLIPEBCHESCN9A | |
| SCHEMBL3346359 | 0.90 | MGLL (0.53) | MGLLLIPEBCHESCN9A | |
| SCHEMBL3350669 | 0.90 | MGLL (0.53) | MGLLLIPEBCHESCN9A | |
| SCHEMBL3346338 | 0.90 | MGLL (0.53) | MGLLLIPEBCHESCN9A | |
| SCHEMBL2424408 | 0.89 | MGLL (0.51) | MGLL | |
| SCHEMBL2425987 | 0.89 | MGLL (0.51) | MGLL | |
| SCHEMBL2340103 | 0.88 | SCN9A (0.51) | MGLLLIPEBCHESCN9A | |
| SCHEMBL2424290 | 0.86 | MGLL (0.49) | MGLL | |
| SCHEMBL2427031 | 0.84 | MGLL (0.57) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367830-A1 | 1-OXA-8-AZASPIRO [4, 5] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | Pfizer Inc. (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | PFIZER INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | FAAH, FAAH2, FFAR1 | MGLL 246/4885LIPE 848/4885BCHE 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.