SCHEMBL33464

SCHEMBL33464

CCC(=O)NC(C)(C)C(=O)N1CC1C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.34
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13154072 0.69 MEN1 (0.39) MAPTSMN1; SMN2GAA
SCHEMBL673556 0.69 TSHR (0.44) TSHRMAPTSMN1; SMN2PDK1PDK2
SCHEMBL2081025 0.68 KDM4C (0.52) TSHRMAPTSMN1; SMN2GAA
SCHEMBL17147985 0.67 SSTR4 (0.39) MAPTSMN1; SMN2GAA
SCHEMBL18518150 0.66 MEN1 (0.36) SMN1; SMN2
SCHEMBL22233553 0.66 SIGMAR1 (0.32)
SCHEMBL22233465 0.66 SIGMAR1 (0.32)
SCHEMBL217915 0.65
SCHEMBL1234217 0.65
SCHEMBL19151295 0.65 MEN1 (0.34) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067504-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-29 US disclosed
US-8067504-B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-11-29 US disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054115-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH ACYLAZIRIDINE CROSSLINKING AGENTS AAAS, PTK2, MDN1 TSHR 4840/4885MAPT 2592/4885SMN1; SMN2 2721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.