Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349847 | 0.89 | MC4R (0.58) | MC4RTAAR1GAAPOLBNPC1 | |
| SCHEMBL3346555 | 0.88 | MC4R (0.68) | MC4RALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL3346234 | 0.83 | MC4R (0.71) | MC4RTAAR1GAAPOLBALDH1A1 | |
| SCHEMBL3346376 | 0.83 | MC4R (0.63) | MC4RTAAR1GAAPOLBNPC1 | |
| SCHEMBL22178742 | 0.83 | MC4R (0.88) | MC4RTAAR1GAAPOLBALDH1A1 | |
| SCHEMBL3353142 | 0.82 | MC4R (0.62) | MC4RTAAR1GAAPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL22160650 | 0.81 | MC4R (0.86) | MC4RTAAR1GAAPOLBALDH1A1 | |
| SCHEMBL3346679 | 0.80 | MC4R (0.59) | MC4RTAAR1GAAPOLBNPC1 | |
| SCHEMBL1819481 | 0.79 | SLC6A3 (0.47) | MC4RPOLBDPP4 | |
| SCHEMBL1819484 | 0.79 | SLC6A3 (0.47) | MC4RPOLBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |