Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346495 | 0.89 | DPP4 (0.50) | MC4RTAAR1ALDH1A1GLAROCK2 | |
| SCHEMBL3346447 | 0.89 | MC4R (0.63) | MC4RTAAR1ALDH1A1GLACASP1 | |
| SCHEMBL3346679 | 0.85 | MC4R (0.59) | MC4RTAAR1ALDH1A1GLACASP1 | |
| SCHEMBL3346376 | 0.84 | MC4R (0.63) | MC4RTAAR1ALDH1A1GLACASP1 | |
| SCHEMBL3353142 | 0.83 | MC4R (0.62) | MC4RTAAR1ALDH1A1GLACASP1 | |
| SCHEMBL3346234 | 0.80 | MC4R (0.71) | MC4RTAAR1ALDH1A1ROCK2POLB | |
| SCHEMBL3349714 | 0.79 | MC4R (0.57) | MC4RTAAR1ALDH1A1GLACASP1 | |
| SCHEMBL22178742 | 0.79 | MC4R (0.88) | MC4RTAAR1ALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL22160650 | 0.78 | MC4R (0.86) | MC4RTAAR1ALDH1A1POLBGAA | |
| SCHEMBL13365133 | 0.77 | ROCK2 (0.48) | ROCK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |