Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346724 | 0.84 | GRM5 (0.46) | DYRK1A | |
| SCHEMBL3346215 | 0.82 | DYRK1A (0.38) | DYRK1ASCN5ATGFBR1 | |
| SCHEMBL3351404 | 0.78 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1 | |
| SCHEMBL3347287 | 0.77 | DYRK1A (0.44) | DYRK1ASCN5ATGFBR1 | |
| SCHEMBL3347351 | 0.76 | SCN5A (0.31) | SCN5A | |
| SCHEMBL3347810 | 0.76 | — | — | |
| SCHEMBL3347239 | 0.76 | DYRK1A (0.45) | DYRK1ASCN5ATGFBR1 | |
| SCHEMBL3352946 | 0.76 | DYRK1A (0.40) | DYRK1ASCN5ATGFBR1 | |
| SCHEMBL3348904 | 0.76 | TGFBR1 (0.46) | DYRK1ASCN5ATGFBR1 | |
| SCHEMBL3347616 | 0.75 | DYRK1A (0.40) | DYRK1ASCN5ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |