Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 6/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346211 | 0.88 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1GRM5 | |
| SCHEMBL3347324 | 0.86 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1GRM5 | |
| SCHEMBL3347271 | 0.86 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1GRM5 | |
| SCHEMBL3346913 | 0.86 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1GRM5PIK3CD | |
| SCHEMBL3346476 | 0.85 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1GRM5 | |
| SCHEMBL3351404 | 0.84 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1GRM5NPC1 | |
| SCHEMBL3347287 | 0.83 | DYRK1A (0.44) | DYRK1ASCN5ATGFBR1GRM5RAB9A | |
| SCHEMBL3347011 | 0.83 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1GRM5 | |
| SCHEMBL3346973 | 0.83 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1GRM5 | |
| SCHEMBL3346984 | 0.83 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |