Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346536 | 1.00 | MGLL (0.48) | MGLLFFAR1MRGPRX4MAOBHRH3 | |
| SCHEMBL3347944 | 0.89 | MGLL (0.53) | MGLLFFAR1MAOBNAAA | |
| SCHEMBL2425943 | 0.89 | MGLL (0.53) | MGLLFFAR1MAOBNAAA | |
| SCHEMBL2425979 | 0.87 | YAP1 (0.49) | MGLL | |
| SCHEMBL18446074 | 0.84 | MGLL (0.50) | MGLL | |
| SCHEMBL3346282 | 0.81 | MGLL (0.51) | MGLL | |
| SCHEMBL3350922 | 0.81 | MGLL (0.51) | MGLL | |
| SCHEMBL3346286 | 0.81 | MGLL (0.51) | MGLL | |
| SCHEMBL27037680 | 0.79 | MRGPRX4 (0.57) | MRGPRX4HRH3TP53HTTL3MBTL1 | |
| SCHEMBL18445935 | 0.78 | FFAR1 (0.47) | MGLLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |