Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL17749556 | 0.97 | ALDH1A1 (0.32) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL2231830 | 0.94 | ALDH1A1 (0.33) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL486485 | 0.83 | TSHR (0.31) | ALDH1A1LMNATSHR | |
| Phosphine SCHEMBL28531842 | 0.80 | TSHR (0.35) | TSHR | |
| Fluoride SCHEMBL12079669 | 0.80 | — | — | |
| SCHEMBL29201858 | 0.78 | ALDH1A1 (0.34) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL14702928 | 0.78 | ALDH1A1 (0.34) | ALDH1A1LMNACYP3A4ALOX15TSHR | |
| SCHEMBL2871050 | 0.78 | — | — | |
| SCHEMBL16369496 | 0.75 | NPSR1 (0.32) | — | |
| SCHEMBL575661 | 0.73 | ALDH1A1 (0.32) | ALDH1A1LMNACYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163471-A | Preparation method of long-chain homoserine derivative | 南京华狮新材料有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-103201280-B | The compositions of suppression JAK approach and method | 里格尔药品股份有限公司 | 2016-08-10 | — | — | CN | claimed |
| US-12398160-B2 | Cot modulators and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2025-08-26 | — | — | US | disclosed |
| US-20240217936-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2024-07-04 | — | — | US | disclosed |
| EP-4375279-A2 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3983064-B1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES INC (US) | 2024-03-06 | — | — | EP | disclosed |
| US-20240058768-A1 | MEMBRANE FOR WATER FILTRATION | AQUAPORIN A/S (DK) | 2024-02-22 | — | — | US | disclosed |
| CN-117030773-B | Nuclear magnetism quantitative detection method of di-tert-butyl chloromethyl phosphate | 瀚盟测试科技（天津）有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20240043458-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2024-02-08 | — | — | US | disclosed |
| EP-4317135-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | West China Hospital, Sichuan University (CN) | 2024-02-07 | — | — | EP | disclosed |
| US-20240024338-A1 | CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USE | ABBVIE INC (US) | 2024-01-25 | — | — | US | disclosed |
| US-6562266-B2 | Composite membrane and method for making the same | DOW GLOBAL TECHNOLOGIES INC. | 2003-05-13 | — | — | US | disclosed |
| CN-1398247-A | Colchicol derivatives as vascular damaging agents | ANGIOGENE PHARM LTD (GB) | 2003-02-19 | — | — | CN | disclosed |
| EP-1276551-A2 | COMPOSITE MEMBRANE AND METHOD FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20020113008-A1 | Composite membrane and method for making the same | THE DOW CHEMICAL COMPANY | 2002-08-22 | — | — | US | disclosed |
| US-6337018-B1 | COATING POROUS SUPPORT WITH SOLUTION OF POLYFUNCTIONAL AMINE AND SOLUTION OF POLYFUNCTIONAL ACYL HALIDE WHICH REACT TO FORM POLYAMIDE LAYER, INCLUDING STEP OF CONTACTING PHOSPHOROUS COMPOUND WITH ACYL HALIDE BEFORE REACTING WITH AMINE | THE DOW CHEMICAL COMPANY | 2002-01-08 | — | — | US | disclosed |
| US-20010050252-A1 | Composite membrane and method for making the same | DOW GLOBAL TECHNOLOGIES LLC | 2001-12-13 | — | — | US | disclosed |
| WO-2001078882-A2 | COMPOSITE MEMBRANE AND METHOD FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-10-25 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12398160-B2 | Cot modulators and methods of use thereof | BRDT, THRB, HCCS | ALDH1A1 2149/4885LMNA 3781/4885CYP3A4 4332/4885 |
| US-20240217936-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, WASF2, CYP3A5 | ALDH1A1 957/4885LMNA 2973/4885CYP3A4 10/4885 |
| US-20240024338-A1 | CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USE | COMT, SNCA, PARK7 | ALDH1A1 694/4885LMNA 3396/4885CYP3A4 381/4885 |
| US-20240043458-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | ALDH1A1 2149/4885LMNA 3781/4885CYP3A4 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.