SCHEMBL3346776

SCHEMBL3346776

NCCCCCSSCCCCCN

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.57
TSHR P16473 3/20 0.57
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA3 P07451 2/20 0.57
CA4 P22748 2/20 0.57
CA6 P23280 2/20 0.57
CA5A P35218 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA5B Q9Y2D0 2/20 0.57
LMNA P02545 1/20 0.57
BLM P54132 1/20 0.57
NFKB1 P19838 1/20 0.50
THPO P40225 1/20 0.50
MAPT P10636 2/20 0.47
EHMT2 Q96KQ7 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3350152 1.00 DNM1 (0.57) DNM1TSHRCA12CA1CA2
SCHEMBL3348447 1.00 DNM1 (0.57) DNM1TSHRCA12CA1CA2
SCHEMBL3350257 1.00 DNM1 (0.57) DNM1TSHRCA12CA1CA2
SCHEMBL3355384 1.00 DNM1 (0.57) DNM1TSHRCA12CA1CA2
Hydrochloric Acid SCHEMBL10808301 0.97 DNM1 (0.53) DNM1TSHRCA12CA1CA2
Hydrochloric Acid SCHEMBL5325306 0.97 DNM1 (0.53) DNM1TSHRCA12CA1CA2
Hydrochloric Acid SCHEMBL10810690 0.97 DNM1 (0.53) DNM1TSHRCA12CA1CA2
Hydrochloric Acid SCHEMBL10809136 0.97 DNM1 (0.53) DNM1TSHRCA12CA1CA2
SCHEMBL3347712 0.96 NFKB1 (0.54) DNM1TSHRCA12CA1CA2
SCHEMBL11281182 0.94 TSHR (0.62) DNM1TSHRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150150994-A1 LIVER TARGETED DRUG DELIVERY SYSTEMS USING METAL NANOPARTICLES AND PREPARING METHOD THEREOF POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-06-04 US claimed
US-11718698-B2 Polyolefin grafted polydiene polymers, and methods of making and using same BRIDGESTONE CORPORATION (JP) 2023-08-08 US disclosed
US-20210230420-A1 Polyolefin Grafted Polydiene Polymers, And Methods Of Making And Using Same BRIDGESTONE CORPORATION (JP) 2021-07-29 US disclosed
EP-3397666-B1 POLYOLEFIN GRAFTED POLYDIENE POLYMERS, AND METHODS OF MAKING AND USING SAME BRIDGESTONE CORP (JP) 2020-08-26 EP disclosed
CN-108473635-B Polyolefin grafted polydiene polymers and methods of making and using the same 株式会社普利司通 2020-08-25 CN disclosed
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP disclosed
US-20180362695-A1 Polyolefin Grafted Polydiene Polymers, And Methods Of Making And Using Same BRIDGESTONE CORPORATION (JP) 2018-12-20 US disclosed
EP-3397666-A1 POLYOLEFIN GRAFTED POLYDIENE POLYMERS, AND METHODS OF MAKING AND USING SAME Bridgestone Corporation (JP) 2018-11-07 EP disclosed
WO-2017117325-A1 POLYOLEFIN GRAFTED POLYDIENE POLYMERS, AND METHODS OF MAKING AND USING SAME BRIDGESTONE CORPORATION (JP) 2017-07-06 WO disclosed
US-20150150994-A1 LIVER TARGETED DRUG DELIVERY SYSTEMS USING METAL NANOPARTICLES AND PREPARING METHOD THEREOF POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-06-04 US disclosed
WO-1998040422-A1 REDUCED TEMPERATURE CURING OF ACETYLENIC POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-09-17 WO disclosed
EP-0504321-B1 ENHANCED CAPTURE OF TARGET NUCLEIC ACID BY THE USE OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMERS MICROPROBE CORP (US) 1997-05-07 EP disclosed
EP-0445588-B1 Method for preparing polyarylene sulfide-polyimide copolymers GEN ELECTRIC (US) 1994-01-05 EP disclosed
US-5239052-A Heating aromatic disulfide in the presence of an aromatic halide HAY ALLAN S (CA) 1993-08-24 US disclosed
EP-0504321-A4 ENHANCED CAPTURE OF TARGET NUCLEIC ACID BY THE USE OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMERS 1993-07-14 EP disclosed
US-5177183-A Reaction of a halophenyl disulfide to form polyphenylene thioether HAY ALLAN S (CA) 1993-01-05 US disclosed
EP-0504321-A1 ENHANCED CAPTURE OF TARGET NUCLEIC ACID BY THE USE OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMERS. MICROPROBE CORP (US) 1992-09-23 EP disclosed
EP-0445588-A1 Method for preparing polyarylene sulfide-polyimide copolymers GENERAL ELECTRIC COMPANY (US) 1991-09-11 EP disclosed
WO-1991008307-A1 ENHANCED CAPTURE OF TARGET NUCLEIC ACID BY THE USE OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMERS MICROPROBE CORPORATION (US) 1991-06-13 WO disclosed
WO-1990001564-A1 METHODS FOR MULTIPLE TARGET ANALYSES THROUGH NUCLEIC ACID HYBRIDIZATION MICROPROBE CORPORATION (US) 1990-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150150994-A1 LIVER TARGETED DRUG DELIVERY SYSTEMS USING METAL NANOPARTICLES AND PREPARING METHOD THEREOF FABP1, CD44, HDGF DNM1 2960/4885TSHR 852/4885CA12 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.