SCHEMBL3346786

SCHEMBL3346786

OCC#Cc1csc(CF)n1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3348245 0.77
SCHEMBL3353813 0.74 GRM5 (0.68) GRM5
SCHEMBL6750170 0.70 GRM5 (0.39) GRM5
SCHEMBL3898599 0.66
SCHEMBL3901343 0.64 GRM5 (0.33) GRM5
SCHEMBL3347186 0.64 GRM5 (0.37) GRM5
SCHEMBL15483095 0.63 GRM5 (0.53) GRM5
SCHEMBL103565 0.62
SCHEMBL7902749 0.62
SCHEMBL5742146 0.62 ALDH1A1 (0.42) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010063487-A1 PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE MERZ PHARMA GMBH & CO. KGAA (DE) 2010-06-10 WO disclosed