Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103337 | 0.86 | GRM5 (0.42) | GRM5TRPV3 | |
| SCHEMBL5742146 | 0.82 | ALDH1A1 (0.42) | GRM5ALDH1A1 | |
| SCHEMBL5259209 | 0.82 | GRM5 (0.41) | GRM5TRPV3 | |
| SCHEMBL103656 | 0.79 | GRM5 (0.42) | GRM5TRPV3 | |
| SCHEMBL874999 | 0.78 | TRPV3 (0.33) | GRM5TRPV3ALDH1A1 | |
| SCHEMBL22031490 | 0.78 | ALDH1A1 (0.37) | GRM5TRPV3ALDH1A1 | |
| SCHEMBL3354041 | 0.77 | KCNH2 (0.33) | — | |
| SCHEMBL5258543 | 0.77 | GRM5 (0.66) | GRM5 | |
| SCHEMBL103768 | 0.76 | CHRNB2 (0.43) | GRM5TRPV3 | |
| SCHEMBL25280190 | 0.74 | SOS2 (0.41) | GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |