SCHEMBL334679

SCHEMBL334679

CC(C)[C@H](N)C(=O)N[C@H](C(N)=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR88 Q9GZN0 2/20 0.49
CTRB1 P17538 2/20 0.44
DPP4 P27487 1/20 0.42
FAP Q12884 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
DPP7 Q9UHL4 1/20 0.42
PRCP P42785 2/20 0.42
CNR1 P21554 1/20 0.41
TACR3 P29371 1/20 0.41
LTA4H P09960 1/20 0.41
ANPEP P15144 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.41
ALOX5 P09917 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961809 0.87 CTRB1 (0.58) GPR88CTRB1CNR1TACR3LTA4H
SCHEMBL19652273 0.85 GPR88 (0.52) GPR88CTRB1CNR1TACR3LTA4H
SCHEMBL14269017 0.85 GPR88 (0.52) GPR88CTRB1CNR1TACR3LTA4H
SCHEMBL7316998 0.84 GPR88 (0.50) GPR88CTRB1TACR3MEN1KMT2A
SCHEMBL7316994 0.84 GPR88 (0.50) GPR88CTRB1TACR3MEN1KMT2A
SCHEMBL12310888 0.84 GPR88 (0.50) GPR88CTRB1TACR3MEN1KMT2A
SCHEMBL7315864 0.81 MEN1 (0.60) PRCPMEN1KMT2ALMNAMMP9
SCHEMBL13479489 0.81 MEN1 (0.60) PRCPMEN1KMT2ALMNAMMP9
SCHEMBL7311069 0.81 LMNA (0.51) CTRB1DPP4FAPDPP8DPP9
SCHEMBL7318689 0.81 LMNA (0.51) CTRB1DPP4FAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097582-B2 Peptide derivatives useful as antimicrobial agents and for treating wounds NEOBIOTICS AB (SE) 2012-01-17 US disclosed