Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347011 | 0.86 | DYRK1A (0.41) | DYRK1ATGFBR1SCN5AGRM5IKBKB | |
| SCHEMBL3346984 | 0.86 | DYRK1A (0.41) | DYRK1ATGFBR1SCN5AGRM5IKBKB | |
| SCHEMBL3347239 | 0.83 | DYRK1A (0.45) | DYRK1ATGFBR1SCN5AGRM5 | |
| SCHEMBL3351404 | 0.80 | DYRK1A (0.42) | DYRK1ATGFBR1SCN5AGRM5 | |
| SCHEMBL3347271 | 0.79 | DYRK1A (0.42) | DYRK1ATGFBR1SCN5AGRM5IKBKB | |
| SCHEMBL3347287 | 0.79 | DYRK1A (0.44) | DYRK1ATGFBR1SCN5AGRM5 | |
| SCHEMBL3345917 | 0.77 | GRM5 (0.44) | DYRK1ATGFBR1SCN5AGRM5 | |
| SCHEMBL3346211 | 0.76 | DYRK1A (0.41) | DYRK1ATGFBR1SCN5AGRM5 | |
| SCHEMBL3346476 | 0.76 | DYRK1A (0.41) | DYRK1ATGFBR1SCN5AGRM5IKBKB | |
| SCHEMBL3352946 | 0.75 | DYRK1A (0.40) | DYRK1ATGFBR1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |