Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347239 | 0.85 | DYRK1A (0.45) | DYRK1ASCN5AGRM5TGFBR1 | |
| SCHEMBL3347287 | 0.81 | DYRK1A (0.44) | DYRK1ASCN5AGRM5TGFBR1TDP1 | |
| SCHEMBL3346211 | 0.81 | DYRK1A (0.41) | DYRK1ACYP2A6SCN5AGRM5TGFBR1 | |
| SCHEMBL3347324 | 0.79 | DYRK1A (0.42) | DYRK1ASCN5AGRM5TGFBR1L3MBTL1 | |
| SCHEMBL3347271 | 0.79 | DYRK1A (0.42) | DYRK1ASCN5AGRM5TGFBR1IKBKB | |
| SCHEMBL3346913 | 0.79 | DYRK1A (0.42) | DYRK1ASCN5AGRM5TGFBR1 | |
| SCHEMBL3346767 | 0.78 | GRM5 (0.46) | DYRK1ACYP2A6SCN5AGRM5TDP1 | |
| SCHEMBL3351404 | 0.77 | DYRK1A (0.42) | DYRK1ASCN5AGRM5TGFBR1 | |
| SCHEMBL3347616 | 0.77 | DYRK1A (0.40) | DYRK1ACYP2A6SCN5ATGFBR1 | |
| SCHEMBL3346724 | 0.77 | GRM5 (0.46) | DYRK1AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |