Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346218 | 0.91 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1PIK3CDMAPT | |
| SCHEMBL3346918 | 0.90 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1PIK3CDMAPT | |
| SCHEMBL3346482 | 0.88 | DYRK1A (0.45) | DYRK1ASCN5ATGFBR1PIK3CDMAPT | |
| SCHEMBL3347294 | 0.87 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1MAPTKMT2A | |
| SCHEMBL3351413 | 0.86 | DYRK1A (0.40) | DYRK1ASCN5ATGFBR1PIK3CDMAPT | |
| SCHEMBL3346989 | 0.85 | DYRK1A (0.39) | DYRK1ASCN5ATGFBR1PIK3CDALDH1A1 | |
| SCHEMBL3346502 | 0.76 | CDK2 (0.36) | — | |
| SCHEMBL3347248 | 0.75 | PIM1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5121363 | 0.67 | BRAF (0.36) | MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL3162678 | 0.67 | DYRK1A (0.65) | DYRK1ASCN5ATGFBR1PIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |