Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346918 | 0.86 | DYRK1A (0.41) | DYRK1ASCN5ATGFBR1ALDH1A1HPGD | |
| SCHEMBL3347243 | 0.85 | DYRK1A (0.44) | DYRK1ASCN5ATGFBR1ALDH1A1HPGD | |
| SCHEMBL3351413 | 0.83 | DYRK1A (0.40) | DYRK1ASCN5ATGFBR1ALDH1A1HPGD | |
| SCHEMBL3346482 | 0.83 | DYRK1A (0.45) | DYRK1ASCN5ATGFBR1ALDH1A1HPGD | |
| SCHEMBL3346218 | 0.83 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1ALDH1A1HPGD | |
| SCHEMBL3347294 | 0.81 | DYRK1A (0.42) | DYRK1ASCN5ATGFBR1ALDH1A1HPGD | |
| SCHEMBL3351756 | 0.78 | CCNE1 (0.34) | — | |
| SCHEMBL3353912 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL3346924 | 0.64 | PDE2A (0.32) | — | |
| SCHEMBL3347604 | 0.64 | PIM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |