Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343687 | 0.89 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL3343988 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3348010 | 0.86 | HCRTR1 (0.42) | HCRTR1HCRTR2TRPM8 | |
| SCHEMBL3350764 | 0.85 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL2635417 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL3417488 | 0.79 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL3415817 | 0.79 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL3348068 | 0.78 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL2057620 | 0.78 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL980677 | 0.77 | PIN1 (0.50) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038200-A1 | OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-08 | — | — | WO | claimed |
| WO-2010038200-A1 | OXAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-08 | — | — | WO | disclosed |