Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.41 |
| ▸ | TUBB | P07437 | 4/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015152 | 0.83 | MIF (0.57) | PTPN1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL13660015 | 0.81 | MIF (0.51) | PTPN1ALDH1A1LMNAHSD17B10TUBB4A | |
| SCHEMBL5689279 | 0.81 | TUBB4A (0.49) | PTPN1HSD17B10TUBB4ATUBBTUBA3C | |
| SCHEMBL13644528 | 0.79 | USP2 (0.53) | PTPN1ALDH1A1LMNAHSD17B10PTAFR | |
| SCHEMBL13362374 | 0.79 | USP2 (0.53) | PTPN1ALDH1A1LMNAHSD17B10PTAFR | |
| SCHEMBL13644516 | 0.77 | ALDH1A1 (0.56) | PTPN1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL5686355 | 0.76 | TUBB4A (0.52) | PTPN1ALDH1A1LMNAHSD17B10TUBB4A | |
| SCHEMBL12651372 | 0.74 | ALDH1A1 (0.46) | PTPN1ALDH1A1LMNAHSD17B10PTAFR | |
| SCHEMBL13644519 | 0.72 | PTPN1 (0.62) | PTPN1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL17366133 | 0.71 | TUBB4A (0.47) | PTPN1ALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058417-A1 | ISOXAZOLE/ISOXAZOLINE/COMBRETASTATIN LINKED DIHYDROQUINAZOLINONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-05-27 | — | — | WO | disclosed |