Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318901 | 0.89 | SCN1A (0.41) | SCN1ASCN2ASCN3AANPEPCYP2D6 | |
| SCHEMBL4751813 | 0.83 | CYP2D6 (0.43) | CYP2D6CYP2C19CACNA1GALDH1A1 | |
| SCHEMBL20711383 | 0.81 | CYP2D6 (0.37) | SCN1ASCN2ASCN3AANPEPCYP2D6 | |
| SCHEMBL27249527 | 0.79 | TSHR (0.54) | SCN1ASCN2ASCN3ACA12CA7 | |
| SCHEMBL26064326 | 0.78 | MAOA (0.46) | CYP2C19CA2MAOAMAOBPAOX | |
| SCHEMBL24482451 | 0.78 | CACNA1G (0.34) | SCN1ASCN2ASCN3AANPEPCYP2D6 | |
| SCHEMBL6516711 | 0.77 | ADRA1A (0.48) | CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL642265 | 0.76 | CYP2D6 (0.38) | SCN1ASCN2ASCN3AANPEPCYP2D6 | |
| SCHEMBL8279519 | 0.76 | EPHX1 (0.36) | SCN1ASCN2ASCN3AANPEPCYP2D6 | |
| SCHEMBL9624660 | 0.75 | HRH4 (0.47) | SCN1ASCN2ASCN3AANPEPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | SCN1A 3581/4885SCN2A 4011/4885SCN3A 3506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.