SCHEMBL334837

SCHEMBL334837

O=C(NCc1ccccc1)OCC1CO1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCHE P06276 9/20 0.59
MGLL Q99685 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1301025 0.84 BCHE (0.49) BCHE
SCHEMBL17346689 0.81 PTGIR (0.52) BCHE
SCHEMBL11324562 0.78 PTGIR (0.56) BCHEMGLL
SCHEMBL3593285 0.76 MGLL (0.88) MGLL
SCHEMBL633304 0.76 LMNA (0.55)
SCHEMBL633303 0.76 LMNA (0.55)
SCHEMBL6154117 0.76 LMNA (0.55)
SCHEMBL27663215 0.75 CHRM3 (0.58) BCHE
SCHEMBL19716546 0.75 PLAU (0.54) BCHE
Benzyl Benzylcarbamate SCHEMBL1136818 0.75 PLAU (0.70)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
EP-1985620-A1 10a-AZALIDE COMPOUND TAISHO PHARMACEUTICAL CO., LTD (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 BCHE 1393/4885MGLL 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.