Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1172351 | 0.73 | BACE1 (0.38) | — | |
| SCHEMBL3695481 | 0.69 | — | — | |
| SCHEMBL1172224 | 0.68 | BACE1 (0.32) | — | |
| SCHEMBL1171736 | 0.67 | KDM4E (0.48) | — | |
| SCHEMBL1171746 | 0.67 | CTSD (0.32) | — | |
| SCHEMBL1171761 | 0.67 | APP (0.32) | — | |
| SCHEMBL1172133 | 0.66 | BACE1 (0.39) | — | |
| SCHEMBL4462368 | 0.65 | HTR5A (0.32) | — | |
| SCHEMBL9848852 | 0.64 | — | — | |
| SCHEMBL6204888 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101686675-A | Compound (I) | SMITHKLINE BEECHAM CORP | 2010-03-31 | — | — | CN | claimed |
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
| CN-101686675-A | Compound (I) | SMITHKLINE BEECHAM CORP | 2010-03-31 | — | — | CN | disclosed |
| EP-1725540-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005095359-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-13 | — | — | WO | disclosed |