Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.72 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 11/20 | 0.64 |
| ▸ | RAB9A | P51151 | 11/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | KLK7 | P49862 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329390 | 0.89 | MAP3K5 (0.83) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL5713530 | 0.87 | MAP3K5 (0.75) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL2483622 | 0.86 | MAP3K5 (0.77) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL3347489 | 0.85 | MAP3K5 (0.63) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL12199362 | 0.85 | MAP3K5 (0.76) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL12225800 | 0.85 | MAP3K5 (0.76) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL12199335 | 0.85 | MAP3K5 (0.76) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL2485047 | 0.84 | SCD (0.82) | DYRK1ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3347250 | 0.84 | RAB9A (0.67) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 | |
| SCHEMBL12199491 | 0.82 | MAP3K5 (0.72) | MAP3K5DYRK1ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |