Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630556 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDAKR1C3AKR1C2PPARG | |
| SCHEMBL30469528 | 0.74 | RXRA (0.51) | ALDH1A1HPGDAKR1C3AKR1C2PPARG | |
| SCHEMBL21609788 | 0.74 | RXRA (0.51) | ALDH1A1HPGDAKR1C3AKR1C2PPARG | |
| SCHEMBL21818224 | 0.74 | PPARG (0.49) | ALDH1A1HPGDAKR1C3AKR1C2PPARG | |
| SCHEMBL16195647 | 0.73 | DHODH (0.52) | ALDH1A1HPGDAKR1C3AKR1C2PPARG | |
| SCHEMBL14427603 | 0.72 | MEN1 (0.66) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL121673 | 0.71 | AKR1C3 (0.61) | ALDH1A1HPGDAKR1C3AKR1C2 | |
| SCHEMBL1006444 | 0.70 | HTT (0.71) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL3351690 | 0.70 | MEN1 (0.47) | ALDH1A1MEN1KMT2AHTTHPGD | |
| SCHEMBL475665 | 0.70 | HPGD (0.51) | ALDH1A1MEN1KMT2AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |